It's kicking my ass.

这事把我折腾得够呛

I'm struggling like crazy.

我拼命挣扎着

This is doing my head in.

这事让我头疼不已

I'm at my wit's end.

我已经山穷水尽了

It's got me beat.

我被这事打败了

I can't get my head around it.

我真是搞不明白

I'm having a mare.

我正经历着一场噩梦

This is a real pain in the neck.

这真是个令人头痛的麻烦

I'm banging my head against a wall.

我在自讨苦吃

It's driving me up the wall.

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