My head is killing me.

我头疼得要命。

I've got a splitting headache.

我头疼得快裂开了。

My brain feels like it's gonna explode.

我感觉我脑袋要炸了。

I need some Advil, like, right now.

我急需几片布洛芬。

This headache is no joke.

这次头痛可不是开玩笑的。

My dome is pounding.

我的脑袋嗡嗡作响。

I woke up with a massive headache.

我一醒来就头痛得不行。

I can't even think straight.

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